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Echelon Biosciences Research Labs SPHINGOSINE KINASE INHIBITOR (SK1-II) 1 mg
SDP

Supplier:  Echelon Biosciences Research Labs B002410MG

Encompass

2-(p-Hydroxyanilino)-4-(p-chlorophenyl)thiazole (SK1-II) is a cell permeable, potent, and specific inhibitor of sphingosine kinase (IC50 = 0.5 M). The compound does not bind to the ATP-binding site and does not affect the kinase activities of hERK2, hPI3K, or hPKC at concentrations up to 60 M. SK1-II showed anti-tumor properties, inducing apoptosis in a number of cell lines including those that express Pgp or MRP1 drug-transport proteins.nn

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Solubility

nDMSO, >5 mg/mLnn
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Documents
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nnTechnical Data Sheet This item is non returnable

Catalog No. 50-720-004


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