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Cayman Chemical Spike Glycoprotein 1147-1162
SDP

Supplier:  Cayman Chemical 3749110 MG

Encompass_Preferred

An inhibitor of SOICR (IC50 16.8 UM in HEK293 cells expressing RyR2R4496C) inhibits Kir2.1 late INa and ICa in isolated canine cardiomyocytes and IKr in HEK293 cells expressing hERG in hypokalaemic but not normokalaemic conditions at 1 UM an antagonist of TLR4 (IC50 32.55 UM in HEK293 cells expressing the human receptor) inhibits HCN4 in COS-7 cells expressing in HCN4 at 10 UM prevents hypokalaemia-induced ventricular arrhythmia in isolated Langendorff-perfused mouse hearts unlike carvedilol it does not reverse isoproterenol-induced increases in heart rate or decrease resting heart rate in RyR2R4496C-expressing mice

Catalog No. 50-291-7862


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