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AdipoGen Spilanthol
Supplier: AdipoGen AGCN20543M005
Chemical. CAS 25394-57-4. Formula C14H23NO. MW 221.3. Spilanthol is a natural non-toxic compound. It is a sesquiterpene lactone and has been traditionally used in folk medicine. It has sensory properties pungency, tingling, numbing, mouth-watering and is an excellent stable model compound for sensory/chemoreception studies like pellitorine and a biological analog of alpha-sanshool. Spilanthol shows various biological properties, including analgesic, antinociceptive, antioxidant, antifungal, anti-inflammatory, antimutagenic, anti-wrinkle, bacteriostatic, insecticidal, anti-malarial, anti-larvicidal and anti-molluscicidal activities. There have also been reports on its activities as an anticonvulsant, aphrodisiac, pancreatic lipase inhibitor, anti-obesity agent, antimicrobial agent, diuretic, pronangiogenic compound, vasorelaxant, anti-HIV and toothache relief agent. The exact mechanism of action of spilanthol is still not fully understood.
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