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Medchemexpress LLC Spiramycin I | 24916-50-5 | 100 MG
SDP

Supplier:  Medchemexpress LLC HYN7141100MG

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Spiramycin I is a macrolide antibiotic and antiparasitic. It binds to the 50S subunit of the ribosome, blocking the channel for peptide chain synthesis, which leads to inhibitory activity against Gram-positive bacteria. Spiramycin I inhibits B. subtilis, M. luteus, S. aureus, S. epidermidis, and S. pneumoniae with MICs ranging from 0.5-8 μg/mL. It also exhibits cytotoxicity in cancer cells (HeLa, KB, MCF-7, HepG2, and U87) with IC50 values between 30.51 and 34.41 μM.

  • Binds to the 50S subunit of the ribosome
  • Blocks peptide chain synthesis
  • Inhibitory activity against Gram-positive bacteria
  • Inhibits various bacteria including B. subtilis, M. luteus, S. aureus, S. epidermidis, and S. pneumoniae
  • Exhibits cytotoxicity in cancer cells
  • For research use only

Catalog No. 50-004-17615


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