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Apexbio Technology LLC Spironolactone 52-01-7 100mg
Supplier: Apexbio Technology LLC B1378100
Spironolactone (52-01-7) is a small-molecule antagonist targeting mineralocorticoid (aldosterone) and androgen receptors It is designed to block receptor-mediated signaling thereby affecting sodium and potassium balance and pathways related to androgen signaling Spironolactone exerts its biological activity primarily through competitive inhibition of mineralocorticoid and androgen receptors In in vitro studies spironolactone demonstrates antagonistic activity with an IC50 value of 24 nM for mineralocorticoid receptors and 77 nM for androgen receptors Based on these pharmacological properties spironolactone holds research potential in studies of hormone signaling sodium homeostasis and androgen receptor-mediated gene expression in endocrine or cancer research
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