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Medchemexpress LLC SPOP-IN-6b dihydrochloride | 99.7% | 573.51 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY122615B

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SPOP-IN-6b dihydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC50 of 3.58 μM. SPOP-IN-6b dihydrochloride shows IC50s of 2-10.2 μM for A498, Caki-2, Ketr-3, 769-P, 0S-RC-2, and 786-0 cells. SPOP-IN-6b (0.1-3.0 μM; 10 hours) dihydrochloride can suppress SPOP activity, and then increase suppression cancer substrate protein PTEN and DUSP7 content.

  • Potent speckle-type POZ protein (SPOP) inhibitor with an IC50 of 3.58 μM.
  • Shows IC50s of 2-10.2 μM for A498, Caki-2, Ketr-3, 769-P, 0S-RC-2, and 786-0 cells.
  • Can suppress SPOP activity and increase suppression cancer substrate protein PTEN and DUSP7 content.
  • In vivo, it can slow down the growth of tumor by suppressing SPOP.

Catalog No. 50-004-38331


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