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Cayman Chemical SR 142948hydrochlorIde 10mg

Supplier: Cayman Chemical 2391110 MG

An NNRTI active against the wild-type HIV-1 strains LAI SF2 and Ba-L (EC50s 1 4-4 8 nM) but not the HIV-2 strain ROD (EC50 3479 nM) active against 18 HIV-1 strains carrying NNRTI resistance-associated mutations (EC50s 5 nM for all) increases intracellular processing of the viral polyproteins Gag and Gag-Pol and decreases viral particle production in HEK293T cells transfected with a plasmid encoding the NL4 3 infectious molecular clone of HIV-1 at 5 M
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