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Cayman Chemical SR 18292, 2095432-55-4, 10 mg
Supplier: Cayman Chemical 2208410
An inhibitor of PGC-1α, increases acetylation of PGC-1α; decreases mRNA expression of Pck1 and G6Pc in primary hepatocytes following glucagon stimulation; reduces fasting blood glucose and Pck1 expression in the liver in a dietary model of type II diabetes in mice at a dose of 45 mg/kg, i.p, for four days; enhances glucose tolerance and insulin sensitivity in two mouse models of obesity
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