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Cayman Chemical SR 58611AhydrochlorIde 10mg
SDP

Catalog No. 502953880
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A selective β3-AR agonist (EC50 = 3.5 nM in rat colon); minimally active against β1-ARs in rat uterus (EC50 = 499 nM) and inactive against β2-ARs in guinea pig trachea and atrium (EC50s = >10,000 and >30,000 nM, respectively); activates brown fat metabolism through activation of adenylyl cyclase activity and glycerol release in brown adipocytes (EC50s = 20 and 11 nM, respectively); reduces hypothermia produced by apomorphine and reserpine; potentiates toxicity produced by yohimbine; reduces number of escape failures in a learned helplessness model of antidepressant-like activity in rats

Catalog No. 50-295-3880 Supplier Cayman Chemical Supplier No. 1195410 MG
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A selective β3-AR agonist (EC50 = 3.5 nM in rat colon); minimally active against β1-ARs in rat uterus (EC50 = 499 nM) and inactive against β2-ARs in guinea pig trachea and atrium (EC50s = >10,000 and >30,000 nM, respectively); activates brown fat metabolism through activation of adenylyl cyclase activity and glycerol release in brown adipocytes (EC50s = 20 and 11 nM, respectively); reduces hypothermia produced by apomorphine and reserpine; potentiates toxicity produced by yohimbine; reduces number of escape failures in a learned helplessness model of antidepressant-like activity in rats

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