Cayman Chemical SR 717lIthIum salt 10mg

Supplier:  Cayman Chemical 3175910 MG

A flavonoid with diverse biological activities inhibits cisplatin-induced increases in apoptosis and ROS in HEK293 cells at 200 M increases renal GSH levels and SOD and catalase activity and reduces serum creatinine and BUN levels renal IL-1B IL-6 and TNF-a levels apoptosis in kidney tissue and kidney injury in a mouse model of cisplatin-induced nephrotoxicity at 50 mg/kg reduces loss of dopaminergic neurons in the substantia nigra and increases striatal GSH levels and SOD activity in a mouse model of MPTP-induced Parkinsons disease at 50 mg/kg per day reduces motor deficits in a mouse model of Parkinsons disease reduces cell viability of MDA-MB-231 and MCF-7 cells (IC50s 167 9 and 191 6 M respectively) as well as inhibits migration and increases apoptosis at 50 and 200 M reduces tumor growth in an MCF-7 mouse xenograft model at 20 mg/kg every other day for 14 days

Catalog No. 50-299-1167