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Apexbio Technology LLC SR-9243 1613028-81-1 200mg
Supplier: Apexbio Technology LLC A8714200
SR-9243 (CAS 1613028-81-1) is a small-molecule inverse agonist targeting liver X receptors (LXRs) nuclear transcription factors involved in metabolic regulation It is designed to induce LXR corepressor interactions thereby suppressing transcriptional activation of glycolytic and lipogenic enzyme genes SR-9243 exerts its biological activity primarily through inhibition of glycolysis- and lipid biosynthesis-associated gene expression In in vitro assays SR-9243 reduces cancer cell viability and induces apoptosis through caspase 3/7 activation in colorectal cancer cell lines Based on these pharmacological properties SR-9243 holds research potential in investigating metabolic reprogramming in cancer particularly in prostate colon and lung cancer models
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