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Apexbio Technology LLC SR1078 1246525-60-9 200mg
Supplier: Apexbio Technology LLC A3835200
SR1078 (CAS 1246525-60-9) is a small-molecule agonist targeting retinoic acid receptor-related orphan receptors alpha and gamma (ROR and ROR ) It is designed to selectively activate these nuclear receptors thereby regulating transcriptional processes involved in metabolic homeostasis and immune responses SR1078 exerts its biological activity primarily through direct binding to the ligand-binding domains of ROR and ROR promoting receptor-mediated transcription In in vitro studies treatment of HepG2 cells with SR1078 enhances ROR-driven gene expression including upregulation of glucose-6-phosphatase and fibroblast growth factor 21 mRNA levels Based on these pharmacological properties SR1078 holds research potential in studying ROR / -mediated biological pathways and their physiological functions
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