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Medchemexpress LLC SR8278 | 1254944-66-5 | 99.9% | C18H19NO3S2 | 50 MG
Supplier: Medchemexpress LLC HY1441550MG
SR8278 is a REV-ERBα antagonist that inhibits the transcriptional repression activity of REV-ERBα with an EC50 of 0.47 μM. It is utilized to regulate metabolism in organisms, study biological rhythms, and research Duchenne muscular dystrophy and Alzheimer's disease.
- Inhibits REV-ERBα transcriptional repression activity (EC50 of 0.47 μM)
- Regulates metabolism and biological rhythm
- Supports research on Duchenne muscular dystrophy
- Supports research on Alzheimer's disease
- Exerts antidepressant and anxiolytic effects
- Restores circadian rhythm of mood-related behaviors
- Alters REV-ERBα and NURR1 binding activities
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