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Medchemexpress LLC SRT 2183 | 1001908-89-9 | 98.1% | 468.57 | 5 MG
SDP

Catalog No. 5000400772
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SRT 2183 is a selective Sirtuin-1 (SIRT1) activator with an EC1.5 value of 0.36 μM. It induces growth arrest and apoptosis, accompanied by deacetylation of STAT3 and NF-κB, and a reduction in c-Myc protein levels. This product is for research use only and is not sold to patients.

  • Selective Sirtuin-1 (SIRT1) activator with an EC1.5 value of 0.36 μM.
  • Induces growth arrest and apoptosis.
  • Causes deacetylation of STAT3 and NF-κB.
  • Reduces c-Myc protein levels.
  • Inhibits the growth of Reh and Nalm-6 cells in a time- and dose-dependent manner.
  • Induces expression of DNA-damage response genes associated with accumulation of phospho-H2A.X levels.
  • Inhibits RANKL-induced osteoclast differentiation, fusion, and resorptive capacity without affecting osteoclast survival.

Catalog No. 50-004-00772 Supplier Medchemexpress LLC Supplier No. HY197595MG
May include imposed supplier surcharges.
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SRT 2183 is a selective Sirtuin-1 (SIRT1) activator with an EC1.5 value of 0.36 μM. It induces growth arrest and apoptosis, accompanied by deacetylation of STAT3 and NF-κB, and a reduction in c-Myc protein levels. This product is for research use only and is not sold to patients.

  • Selective Sirtuin-1 (SIRT1) activator with an EC1.5 value of 0.36 μM.
  • Induces growth arrest and apoptosis.
  • Causes deacetylation of STAT3 and NF-κB.
  • Reduces c-Myc protein levels.
  • Inhibits the growth of Reh and Nalm-6 cells in a time- and dose-dependent manner.
  • Induces expression of DNA-damage response genes associated with accumulation of phospho-H2A.X levels.
  • Inhibits RANKL-induced osteoclast differentiation, fusion, and resorptive capacity without affecting osteoclast survival.

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