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Apexbio Technology LLC STA-21 111540-00-2 1mg
SDP

Supplier:  Apexbio Technology LLC B61751

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STA-21 (CAS 111540-00-2) is a small-molecule inhibitor targeting STAT3 a transcription factor activated by cytokines such as IL-6 It inhibits STAT3 DNA-binding activity and dimerization thereby modulating downstream signaling pathways associated with Th17 differentiation and inflammatory processes STA-21 exerts its biological activity primarily by suppressing STAT3-mediated IL-17 expression and osteoclast differentiation as well as promoting FoxP3 expression In in vitro studies STA-21 inhibits DU145 cell viability with an IC50 of 12 2 M Based on these pharmacological properties STA-21 holds research potential in the fields of autoimmune and inflammatory disease

Catalog No. 50-000-88092


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