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Apexbio Technology LLC Staurosporine 62996-74-1 10mM (in 1mL DMSO)

Supplier: Apexbio Technology LLC A81925.1

Staurosporine is an alkaloid compound originally isolated from the bacterium Streptomyces staurospores and functions as a broad-spectrum inhibitor of serine/threonine protein kinases It potently inhibits multiple kinases including protein kinase C (PKC) protein kinase A (PKA) epidermal growth factor receptor kinase (EGF-R kinase) calmodulin-dependent protein kinase II (CaMKII) phosphorylase kinase and ribosomal protein S6 kinase Its activity against PKC exhibits an IC50 value of approximately 2 7 nM In biomedical research staurosporine is commonly employed to induce apoptosis in mammalian cancer cell lines and to investigate the roles and signaling pathways of protein kinases
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