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Medchemexpress LLC Stearoylcarnitine | 25597-09-5 | 99.9% | 427.66 | 50 MG
Supplier: Medchemexpress LLC HY11320250MG
Stearoylcarnitine is a fatty ester lipid molecule and an endogenous metabolite. It can act as a PKC inhibitor and accumulates in β cells, leading to arrest of insulin synthesis and energy deficiency in type 2 diabetes mouse models. It also inhibits lecithin cholesterol acyltransferase (LCAT) in rat and rabbit plasma and serves as a metabolomics biomarker for Parkinson's disease. Additionally, it is a less potent inhibitor of GlyT2.
- Functions as an endogenous metabolite.
- Acts as a PKC inhibitor.
- Accumulates in beta cells, impairing insulin synthesis.
- Inhibits lecithin cholesterol acyltransferase (LCAT) in rat and rabbit plasma.
- Serves as a metabolomics biomarker for Parkinson's disease.
- Less potent inhibitor of GlyT2.
- Impairs mitochondrial energy metabolism in MIN6 cells.
- Alters brain acylcarnitine levels in a mouse model of hypoxic-ischemic brain injury.
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