Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. NC0577320

Reprocell Stemolecule Y27632, 10 mg, cell-permeable small molecule, reversible ATP-competitive ROCK inhibitor, white solid, inhibits ROCK1 (220 nM), ROCK2 (300 nM), >97% purity

Catalog No. NC0577320
Encompass

Stemolecule Y27632 is a cell-permeable small molecule that serves as a highly potent and selective inhibitor of Rho-associated kinase (ROCK), specifically targeting ROCK1 and ROCK2. This compound is extensively utilized in stem cell research to enhance the survival and cloning efficiency of dissociated human embryonic stem (ES) cells without compromising their self-renewal properties and pluripotency. Additionally, it improves the survival of ES cell-derived neural precursors during transplantation and significantly enhances cell recovery after cryopreservation when combined with Pifithrin-u.

  • Molecular target: Rho-associated kinase (ROCK)
  • Mechanism of action: Reversible ATP-competitive inhibitor
  • Inhibitory concentration (Ki): ROCK1 220 nM, ROCK2 300 nM
  • Purity: >97% by HPLC
  • Formulation: White solid
  • Solubility: Reconstitute in DMSO
  • Pack size: 10 mg

Catalog No. NC0577320 Supplier Reprocell Supplier No. 04001210
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

Stemolecule Y27632 is a cell-permeable small molecule that serves as a highly potent and selective inhibitor of Rho-associated kinase (ROCK), specifically targeting ROCK1 and ROCK2. This compound is extensively utilized in stem cell research to enhance the survival and cloning efficiency of dissociated human embryonic stem (ES) cells without compromising their self-renewal properties and pluripotency. Additionally, it improves the survival of ES cell-derived neural precursors during transplantation and significantly enhances cell recovery after cryopreservation when combined with Pifithrin-u.

  • Molecular target: Rho-associated kinase (ROCK)
  • Mechanism of action: Reversible ATP-competitive inhibitor
  • Inhibitory concentration (Ki): ROCK1 220 nM, ROCK2 300 nM
  • Purity: >97% by HPLC
  • Formulation: White solid
  • Solubility: Reconstitute in DMSO
  • Pack size: 10 mg

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.