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STEMCELL Technologies StemRegenin 1 (Hydrochloride), Size: 5 mg
Supplier: STEMCELL Technologies 72354
Promote the maintenance and expansion of human hematopoietic stem cells in culture (Boitano et al. Science 2010 Csaszar et al. Cell Stem Cell 2012) with StemRegenin 1 (Hydrochloride). StemRegenin 1 is an antagonist of the aryl hydrocarbon receptor (AHR). It promotes ex vivo expansion of CD34 human hematopoietic stem cells and the generation of CD34 hematopoietic progenitor cells from non-human primate induced pluripotent stem cells. StemRegenin1 is also used in stimulating the differentiation of CD34 hematopoietic progenitor cells into functional human dendritic cells (Thordardottir et al. Stem Cells Dev 2014) and promoting hematopoietic differentiation of induced pluripotent stem cells (iPSCs) (Gori et al. Blood 2012). Together with UM729 it is also used in preventing differentiation of AML cells in culture. StemRegenin 1 is supplied as the hydrochloride salt of the molecule with ≥ 98% purity Molecu
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