Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Apexbio Technology LLC StemRegenin 1 (SR1) 1227633-49-9 200mg
Supplier: Apexbio Technology LLC A8224200
StemRegenin 1 (SR1 CAS 1227633-49-9) is a purine derivative that functions as an antagonist of the aryl hydrocarbon receptor (AhR) SR1 inhibits AhR signaling in CD34 hematopoietic progenitor cells with an IC50 value of approximately 127 nM Studies demonstrate that SR1 promotes the ex vivo expansion of CD34 cells significantly increasing both the number of CD34-expressing hematopoietic stem cells (HSCs) and their engraftment potential in immunodeficient mouse models Additionally SR1 enables differentiation and robust production of multiple dendritic cell subsets including plasmacytoid dendritic cells (pDCs) and BDCA1 /BDCA3 myeloid DCs from CD34 progenitors indicating its utility for dendritic cell research and hematopoietic stem cell biology
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?