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Medchemexpress LLC STING-IN-4 | 2250374-27-5 | C32H46N2O3 | 5 MG
Supplier: Medchemexpress LLC HY1519705MG
STING-IN-4 is a STING inhibitor that inhibits STING expression, thereby reducing the activation of STING and nuclear factor-κB (NF-κB) signaling. It demonstrates anti-inflammatory activity and is suitable for sepsis research.
- Inhibits STING expression
- Reduces activation of STING and nuclear factor-κB (NF-κB) signaling
- Demonstrates anti-inflammatory activity
- Suitable for sepsis research
- Inhibits nitric oxide production in RAW264.7 cells
- Inhibits iNOS expression in RAW264.7 cells
- Reduces STING degradation
- May enhance thermal stabilization of STING
- Inhibits LPS-induced activation of STING/IRF3/NF-κB
- Protects against LPS-induced liver injuries in mice
- Inhibits STING/IRF3/NF-κB activation in septic mice livers
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