Invitrogen™ Human STK23 (MSSK1), GST Tag Recombinant Protein

Catalog No.	Quantity
PV3880	10 μg

Catalog No. PV3880 Supplier Invitrogen™ Supplier No. PV3880

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.

STK23 (MSSK1), also known as SRPK3, is a muscle-specific member of the SRPKs. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

Specifications

• Accession Number: Q9UPE1
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50mM tris with 50% glycerol, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 150mM NaCl and no preservative; pH 7.5
• Gene ID (Entrez): 26576
• Molecular Weight (g/mol): 86.5 kDa
• Name: Human STK23 (MSSK1), GST Tag
• pH Range: 7.5
• Purification Method: Purified
• Quantity: 10 μg
• Storage Requirements: -80°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: MSSK1; MSSK-1; muscle-specific serine kinase 1; muscle-specific serine kinase 1; MSSK1; serine arginine rich protein-specific kinase 3; serine/arginine-rich protein specific kinase 3; serine/arginine-rich protein-specific kinase 3; serine/threonine kinase 23; serine/threonine kinase 23, muscle-specific serine kinase 1 70; serine/threonine-protein kinase 23; serine/threonine-protein kinase SRPK3; SFRS protein kinase 3; Srpk3; SR-protein-specific kinase 3; SRSF protein kinase 3; STK23
• Common Name: SRPK3
• Gene Symbol: SRPK3
• Kinase Family: SRPK Kinase Family
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: GST-tag
• Sequence: Full length
• Content And Storage: -80°C, Avoid Freeze/Thaw Cycles
• Assay Entry: Biochemical phospho-specific activity (no antibody)
• Kinase Group: Ser/Thr Kinases: CMGC Group
• Shipping Condition: Dry Ice
• System Compatibility: Zin-LYTE™
• Tag Position: N-Terminal
• Target Entry: STK23
• Target Gene: SFRS protein kinase 3
• Expression System: Baculovirus
• Protein Family: Kinases & Inhibitors
• Protein Form: Recombinant, Full Length
• Form: Liquid
• Protein Subtype: Serine/Threonine Kinases
• Research Category: Drug Discovery: Signal Transduction