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Cayman Chemical STING Agonist D61, Purity: ≥95%, CAS: 2850251-27-1, 5 mg
SDP

Catalog No. 502917471
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A STING agonist; induces expression of an IFN3-inducible SEAP reporter gene and an IFN-β-inducible reporter gene in cell-based assays (EC50s = 52.9 and 116 nM, respectively); increases the expression of mRNA encoding IFN-β and CXCL10 and phosphorylation of TBK1, IRF3, and STING in THP-1 monocytes at 4, 6, and 8 µM; reduces tumor volume without affecting body weight in a CT26 murine colon cancer model at 0.25 mg/kg every other day

Catalog No. 50-291-7471 Supplier Cayman Chemical Supplier No. 387065 MG
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A STING agonist; induces expression of an IFN3-inducible SEAP reporter gene and an IFN-β-inducible reporter gene in cell-based assays (EC50s = 52.9 and 116 nM, respectively); increases the expression of mRNA encoding IFN-β and CXCL10 and phosphorylation of TBK1, IRF3, and STING in THP-1 monocytes at 4, 6, and 8 µM; reduces tumor volume without affecting body weight in a CT26 murine colon cancer model at 0.25 mg/kg every other day

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