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Cayman Chemical STng M284 varInt PolycLNal 1ea

Supplier: Cayman Chemical 247911 EA

A selective estrogen receptor modulator binds to ERa and ERB (Kis 380 and 410 nM respectively) increases vaginal weight and vaginal epithelial height (ED50s 0.48 and 0.39 mg/kg per day respectively) in an ovariectomized rat model of menopause increases progesterone receptor protein expression in vaginal epithelium and stroma and inhibits 17b-estradiol-induced estrogen response element-mediated transactivation in a reporter assay using MCF-7 cells
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