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Cayman Chemical Stphna yuns Crbn 10mg
Supplier: Cayman Chemical 3617610 MG
An aporphine alkaloid; an antagonist of α7 nAChRs (IC50 = 19.1 µM); inhibits INa in isolated guinea pig ventricular myocytes (IC50 = 283 µM); active against Gram-positive bacteria (MICs = 0.213-0.312 g/L); inhibits the LPS-induced production of TNF-α, IL-6, NO, and PGE2 in RAW 264.7 macrophages at 29.5 µM; inhibits the proliferation of A549, MDA-MB-231, MCF-7, SKOV3, and Caov-3 cells; reduces TNF-α induced invasion and migration of A549 cells; prevents scopolamine-induced memory deficits in the Morris water maze in mice at 25 mg/kg
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