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Cayman Chemical StreptavIdInSureLIght RPE 1ea

Supplier: Cayman Chemical 134341 EA

A prodrug form of candesartan inhibits the angiotensin II-induced pressor response in normotensive rats (ID50 0 069 mg/kg) decreases blood pressure in spontaneously hypertensive and 2K-1C and 1K-1C renal hypertensive rats (ED25s 0 68 0 03 and 0 23 mg/kg respectively) reduces stroke incidence and urinary protein excretion in stroke-prone spontaneously hypertensive rats at 0 1 mg/kg prevents stress-induced tyrosine hydroxylase transcription and increases AT2 receptor expression in the ventrolateral thalamic nucleus in cold-restraint stressed spontaneously hypertensive rats at 10 mg/kg per day
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