Thermo Scientific Chemicals Streptomycin sulfate

Description

Streptomycin sulfate, CAS # 3810-74-0, is the sulfate salt form of streptomycin, and an aminoglycoside with antibacterial activity. It also shows a protein synthesis inhibitory activity.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Streptomycin sulfate is an aminoglycoside sulfate salt derived from Streptomyces griseus that shows antibacterial activity.

• It inhibits initiation and causes misreading of rRNA in protein synthesis. This compound binds to the S12 protein of the bacterial 30S ribosomal subunit, thereby inhibiting peptide elongation and protein synthesis.

Application

• Streptomycin sulfate can be used to study the mechanisms of streptomycin resistance

• This compound can be used in laboratory applications combined with penicillin to inhibit bacterial contamination in in vitro cell culture

• Streptomycin sulfate shows antibiotic activity against Mycobacterium tuberculosis

• This compound can be used as a protein synthesis inhibitor

• It acts against gram-negative and gram-positive bacteria • Streptomycin sulfate also shows a fungicide activity

• It can be used to remove nucleic acids from a biological extract

Specifications

Chemical Identifiers

• CAS: 3810-74-0
• Molecular Formula: C42H84N14O36S3
• Molecular Weight (g/mol): 1457.376
• InChI Key: QTENRWWVYAAPBI-FFCQDDOVSA-N
• PubChem CID: 124080941
• IUPAC Name: 2-[(1R,2S,3S,4S,5R,6S)-3-(diaminomethylideneamino)-4-[(2R,3S,4S,5S)-3-[(2R,3S,4R,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine;2-[(1R,2S,3S,4R,5R,6R)-3-(
• SMILES: CC1C(C(C(O1)OC2C(C(C(C(C2O)O)N=C(N)N)O)N=C(N)N)OC3C(C(C(C(O3)CO)O)O)NC)(C=O)O.CC1C(C(C(O1)OC2C(C(C(C(C2O)O)N=C(N)N)O)N=C(N)N)OC3C(C(C(C(O3)CO)O)O)NC)(C=O)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O

• Type: Streptomycin Sulfate
• Loss on Drying: 7% max.
• Quantity: 5 g
• Solubility Information: Solubility in water: soluble.
• Formula Weight: 1457.4
• Chemical Name or Material: Streptomycin sulfate

Safety and Handling

Hazard Category	Warning
Hazard Statement	GHS H Statement Suspected of damaging the unborn child. Harmful if swallowed. May cause an allergic skin reaction.
Precautionary Statement	GHS P Statement Avoid breathing dust/fume/gas/mist/vapors/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF exposed or concerned: Get medical advice/attention. Obtain special instructions before use. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water.

SDS

RUO – Research Use Only