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Streptozotocin, 97+%

Catalog No. AAJ61601ME
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Catalog No. AAJ61601ME Supplier Thermo Scientific Chemicals Supplier No. J61601ME
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Streptozotocin (streptozocin, CAS # 18883-66-4) is an N-nitrosourea antibiotic produced by Streptomyces achromogenes. | CAS: 18883-66-4 | C8H15N3O7 | 265.222 g/mol

Streptozotocin is used to induce Type 1 diabetes for medicine.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Streptozotocin acts as a bactericidal by alkylating DNA and inhibiting DNA synthesis

• Streptozotocin enters cells through glucose transporter 2

Application

• Streptozotocin induces diabetes in experimental animals and can cause acute liver injury

• It is also useful for research on neuroendocrine tumors and carcinoma cells

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 18883-66-4
Molecular Formula C8H15N3O7
Molecular Weight (g/mol) 265.222
MDL Number MFCD00006607
InChI Key ZSJLQEPLLKMAKR-UHEPRFFZSA-N
Synonym NSC-85998; U-9889
PubChem CID 45357367
IUPAC Name 1-methyl-1-nitroso-3-[(2R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]urea
SMILES CN(C(=O)NC1C(C(C(OC1O)CO)O)O)N=O

Specifications

Type Streptozotocin
Physical Form Powder
Melting Point 121°C
Color White
Quantity 500 mg
Sensitivity Hygroscopic
Beilstein 2060675
Merck Index 14,8832
Solubility Information Soluble in water or 100% ethanol
Formula Weight 265.22
Percent Purity ≥97%
Chemical Name or Material Streptozotocin
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Hazard Category H350
Hazard Statement GHS H Statement
H351
Suspected of causing cancer.
Precautionary Statement P201-P202-P281-P308+P313-P501c
EINECSNumber 242-646-8
RTECSNumber LZ5775000
TSCA No
Recommended Storage Store at -20°C

RUO – Research Use Only

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