Streptozotocin, 97+%

Description

Streptozotocin (streptozocin, CAS # 18883-66-4) is an N-nitrosourea antibiotic produced by Streptomyces achromogenes. | CAS: 18883-66-4 | C8H15N3O7 | 265.222 g/mol

Streptozotocin is used to induce Type 1 diabetes for medicine.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Streptozotocin acts as a bactericidal by alkylating DNA and inhibiting DNA synthesis

• Streptozotocin enters cells through glucose transporter 2

Application

• Streptozotocin induces diabetes in experimental animals and can cause acute liver injury

• It is also useful for research on neuroendocrine tumors and carcinoma cells

Specifications

Chemical Identifiers

• CAS: 18883-66-4
• Molecular Formula: C8H15N3O7
• Molecular Weight (g/mol): 265.222
• MDL Number: MFCD00006607
• InChI Key: ZSJLQEPLLKMAKR-UHEPRFFZSA-N
• Synonym: NSC-85998; U-9889
• PubChem CID: 45357367
• IUPAC Name: 1-methyl-1-nitroso-3-[(2R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]urea
• SMILES: CN(C(=O)NC1C(C(C(OC1O)CO)O)O)N=O

• Type: Streptozotocin
• Physical Form: Powder
• Melting Point: 121°C
• Color: White
• Quantity: 500 mg
• Sensitivity: Hygroscopic
• Beilstein: 2060675
• Merck Index: 14,8832
• Solubility Information: Soluble in water or 100% ethanol
• Formula Weight: 265.22
• Percent Purity: ≥97%
• Chemical Name or Material: Streptozotocin

Safety and Handling

Hazard Category	H350
Hazard Statement	GHS H Statement H351 Suspected of causing cancer.
Precautionary Statement	P201-P202-P281-P308+P313-P501c
EINECSNumber	242-646-8
RTECSNumber	LZ5775000
TSCA	No
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only