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Bachem C-Peptide 1 (rat) Trifluoroacetate

Supplier: Bachem 4045921.1000

C-Peptide 1 (rat) Trifluoroacetate, H-Glu-Val-Glu-Asp-Pro-Gln-Val-Pro-Gln-Leu-Glu-Leu-Gly-Gly-Gly-Pro-Glu-Ala-Gly-Asp-Leu-Gln-Thr-Leu-Ala-Leu-Glu-Val-Ala-Arg-Gln-OH, 41475-27-8, C140H228N38O51, Mr 3259.58, 1mg. Insulin 1 Precursor (57-87) (rat), Preproinsulin 1 (57-87) (rat), Proinsulin 1 (33-63) (rat). Studies of the cellular effects of C-peptide have shown that it binds specifically in a nanomolar concentration range to a G-protein coupled membrane receptor, with subsequent activation of Ca2+-dependent intracellular signaling pathways. This resulted in stimulation of both Na+-K+-ATPase, and endothelial nitric oxide synthase activities. Administration of C-peptide to streptozotocin induced diabetic rats elicited a substantial increase in whole-body glucose turnover.
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