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Apexbio Technology LLC SU 4312 5812-07-7 10mM (in 1mL DMSO)
SDP

Supplier:  Apexbio Technology LLC B67465.1

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SU 4312 (CAS 5812-07-7) is a racemic mixture comprising both (Z)- and (E)-isomers each exhibiting distinct receptor tyrosine kinase inhibitory profiles The (Z)-isomer selectively inhibits platelet-derived growth factor receptor (PDGFR) and vascular endothelial growth factor receptor 2 (VEGFR2/FLK-1) while the (E)-isomer targets PDGFR VEGFR2 epidermal growth factor receptor (EGFR) human epidermal growth factor receptor 2 (HER-2) and insulin-like growth factor 1 receptor (IGF-1R) SU 4312 is widely employed in studies investigating tumor angiogenesis cellular signal transduction pathways and the development of targeted therapies in cancer research

Catalog No. 50-000-90212


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