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Enzo Life Sciences SU11652 (1mg). CAS: 326914-10-7
SDP

Supplier:  Enzo Life Sciences BMLEI4080001

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Potent, ATP-competitive and cell permeable inhibitor of tyrosine kinases (VEGF-R2 IC50=27nM, PDGF-Rβ IC50=3nM). Also inhibits wild-type and all mutant forms of Kit in mast cells (IC50's=10 to 100nM) resulting in cell cycle arrest and apoptosis. Su11652 was also shown to induce autophagy in MCF-7 cells. Alternative name: 5-[5-Chloro-2-oxo-1,2-dihydroindol-(3Z)-ylidenemethyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO (>25 mg/ml). Long Term Storage: -20°C.

Catalog No. 50-201-0785


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