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Bachem Suc-Ala-Ala-Pro-Phe-pNA
Supplier: Bachem 4002299.1000
Suc-Ala-Ala-Pro-Phe-pNA, 70967-97-4, C30H36N6O9, Mr 624.65, 1g. SAAPNA. A readily soluble, specific and sensitive substrate for chymotrypsin and human pancreatic elastase. It is also hydrolyzed by cathepsin G and chymase. Furthermore it is the standard substrate for FK-506 binding proteins (FKBPs, also called macrophilins) and cyclophilins, which belong to the group of peptidyl prolyl cis-trans isomerases (PPIases). Thus, Suc-AAPF-pNA has been used for an uncoupled protease-free assay of PPIase activity.
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