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Medchemexpress LLC Succinimidyl 6-[3-(2-pyridyldithio)propionamido]hexanoate | 158913-22-5 | MFCD00083163 | 98.1% | 425.52 g/mol | C18H23N3O5S2 | 1G
SDP

Supplier:  Medchemexpress LLC HY1243771G

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Succinimidyl 6-[3-(2-pyridyldithio)propionamido]hexanoate is an alkyl/ether-based PROTAC linker containing an N-hydroxysuccinimide (NHS) ester for amine coupling and a pyridyldisulfide moiety for thiol-directed conjugation. It is used in PROTAC and bioconjugation synthesis and features a reducible disulfide that enables controlled cleavage in downstream applications.

  • Provides an NHS ester for efficient conjugation to primary amines.
  • Contains a pyridyldisulfide cleavable disulfide for thiol chemistry.
  • Suitable as a linker in PROTAC and bioconjugation synthesis.
  • Molecular formula C18H23N3O5S2; molecular weight 425.52 g/mol.
  • Soluble in DMSO at approximately 50 mg/mL; may require sonication.
  • Store powder at -20°C for long-term stability; solvent solutions require low-temperature storage.
  • High purity (98.1%) suitable for research applications.

Catalog No. 50-002-38902


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