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Medchemexpress LLC Succinyl phosphonate trisodium salt | 864167-45-3 | 98.0% | 10 MG
Supplier: Medchemexpress LLC HY12688A10MG
Succinyl phosphonate trisodium salt is an α-ketoglutarate dehydrogenase (KGDHC) inhibitor, which effectively inhibits KGDHC in muscle, bacterial, brain, and cultured human fibroblasts. It is also an inhibitor of 2-oxoglutarate dehydrogenase (OGDH), impairing the viability of cancer cells in a cell-specific, metabolism-dependent manner. Additionally, it inhibits glutamate-induced ROS production in glutamate-stimulated hippocampal neurons in situ.
- Effectively inhibits KGDHC in various tissues and cells
- Acts as an OGDH inhibitor, reducing cancer cell viability
- Inhibits glutamate-induced ROS production
- Intended for research use only
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