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Apexbio Technology LLC Sulbactam 68373-14-8 100mg
Supplier: Apexbio Technology LLC B2131100
Sulbactam (CAS 68373-14-8) is a small-molecule inhibitor targeting bacterial -lactamase enzymes It is designed to inhibit -lactamase-mediated hydrolytic inactivation of -lactam antibiotics thereby enhancing antibiotic stability and efficacy Sulbactam exerts its biological activity primarily through competitive irreversible inhibition by covalently binding to the -lactamase active site Experimental studies report an IC50 value in the low micromolar range for inhibition of various bacterial -lactamase enzymes Based on these pharmacological properties Sulbactam holds research potential in investigating resistance mechanisms to -lactam antibiotics assessing combined therapeutic regimens and exploring novel clinical strategies for infections caused by -lactamase-producing pathogens
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