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Cayman Chemical SulfaethoxypyrIdazIn 50mg
SDP

Supplier:  Cayman Chemical 4169850 MG

Encompass_Preferred

An Hsp90 inhibitor binds to the C-terminal domain of Hsp90a and inhibits the protein-protein interaction between the Hsp90a C-terminal domain and PPID decreases cell viability and induces apoptosis in HER2-positive BT474 and SK-BR-3 cells at 0.5-20 UM reduces mammosphere formation by as well as Hsf-1 Hsp70 and Hsp90 protein levels in BT474 cells at 10 UM reduces intratumoral levels of HER2 and ICD-HER2 as well as reduces tumor growth and angiogenesis in a trastuzumab-resistant JIMT-1 mouse xenograft model at 30 mg/kg

Catalog No. 50-294-3840


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