Sulfanilamide, 98%, Thermo Scientific Chemicals

Description

Sulfonamide antibacterial Sulfanilamide is an antibacterial and used in the treatment of vaginal yeast infections. It is a competitive inhibitor of dihydropteroate synthestase to block the synthesis of folic acid. It serves as an intermediate for the preparation of 2,6-disubstituted anilines by electrophilic substitution followed by removal of the sulfonamide blocking group by desulfonation with sulfuric acid.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Sulfonamide antibacterial Sulfanilamide is an antibacterial and used in the treatment of vaginal yeast infections. It is a competitive inhibitor of dihydropteroate synthestase to block the synthesis of folic acid. It serves as an intermediate for the preparation of 2,6-disubstituted anilines by electrophilic substitution followed by removal of the sulfonamide blocking group by desulfonation with sulfuric acid.

Solubility
Soluble in water, acetone, ethanol, glycerol, propylene glycol and hydrochloric acid. Insoluble in chloroform, ether, benzene and petroleum ether.

Notes
Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 63-74-1
• Molecular Formula: C6H8N2O2S
• Molecular Weight (g/mol): 172.202
• MDL Number: MFCD00007939
• InChI Key: FDDDEECHVMSUSB-UHFFFAOYSA-N
• Synonym: sulfanilamide, sulphanilamide, sulfamine, sulphonamide, p-aminobenzenesulfonamide, sulfonylamide, sulfonamide, p-aminobenzenesulfamide, bacteramid, streptasol
• PubChem CID: 5333
• ChEBI: CHEBI:45373
• IUPAC Name: 4-aminobenzenesulfonamide
• SMILES: C1=CC(=CC=C1N)S(=O)(=O)N

• Melting Point: 163°C to 168°C
• Density: 1.08
• Quantity: 500 g
• Beilstein: 511852
• Merck Index: 14,8925
• Solubility Information: Soluble in water,acetone,ethanol,glycerol,propylene glycol and hydrochloric acid. Insoluble in chloroform,ether,benzene and petroleum ether.
• Formula Weight: 172.21
• Percent Purity: 98%
• Chemical Name or Material: Sulfanilamide

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	200-563-4
RTECSNumber	WO8400000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only