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Cayman Chemical SulfIsoxazole 10g

Supplier: Cayman Chemical 2598010 G

A potent and selective inhibitor of Aurora A kinase (IC50s 3.4 and 3400 nM for Aurora A and Aurora B respectively) prevents centrosome separation and reduces phosphorylated Aurora A but not phosphorylated histone H3 levels at the centrosomes reduces the proliferation of HCT116 and HT-29 colorectal carcinoma cells in vitro (IC50s 0.19 and 2.9 M respectively)
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