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Cayman Chemical Sulfo-CynIn 5 5 10mg

Supplier: Cayman Chemical 3736910 MG

An EAAT inhibitor inhibits glutamate uptake in COS-1 cells expressing human EAAT1 or EAAT2 (IC50s 96 and 31 UM respectively) inhibits inward currents induced by L-aspartate in EAAT4-expressing Xenopus oocytes (Ki 0.6 UM) and by L-glutamate in EAAT5-expressing oocytes (Ki 2.5 UM) voltage-clamped at -60 mV intrathecal administration (7.5 and 15 Ug/animal) reduces the number of flinches and shakes in the second phase of the formalin test in rats
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