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Medchemexpress LLC Sulfo DBCO-amine | 2028284-70-8 | 99.0% | 100 MG
Supplier: Medchemexpress LLC HY127056100MG
Sulfo DBCO-amine is an alkyl chain-based PROTAC linker designed for use in the synthesis of PROTACs. It functions as a click chemistry reagent, containing a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules that possess Azide groups. PROTACs themselves are composed of two distinct ligands connected by a linker, with one ligand targeting an E3 ubiquitin ligase and the other targeting a specific protein, enabling the selective degradation of target proteins through the intracellular ubiquitin-proteasome system.
- Alkyl chain-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains a DBCO group for SPAAC with Azide groups
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