Medchemexpress LLC Sulfo DBCO-amine | 2028284-70-8 | 99.0% | 25 MG

Supplier:  Medchemexpress LLC 25MGHY127056

Sulfo DBCO-amine is an alkyl chain-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing a DBCO group capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules that possess Azide groups. PROTACs themselves consist of two distinct ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein, enabling selective degradation of target proteins through the intracellular ubiquitin-proteasome system.

• Alkyl chain-based PROTAC linker.
• Utilized in the synthesis of PROTACs.
• Functions as a click chemistry reagent.
• Contains a DBCO group for strain-promoted alkyne-azide cycloaddition (SPAAC).
• Enables selective degradation of target proteins through the intracellular ubiquitin-proteasome system.
• Suitable for cancer and cancer targeted therapy research.

Catalog No. 50-003-41415