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Medchemexpress LLC Sulfo-SPDB-DM4 | 1626359-59-8 | 99.9% | 1075.66 g·mol⁻¹ | C46H63ClN4O17S3 | 1 MG
Supplier: Medchemexpress LLC HY1011411MG
sulfo-SPDB-DM4 is a drug-linker conjugate for antibody-drug conjugate (ADC) research that connects the maytansinoid cytotoxin DM4 to biomolecules via a cleavable sulfo-SPDB disulfide linker, allowing intracellular release of the payload after internalization. Intended for research use only, it is supplied as a high-purity analytical material for conjugation and characterization workflows.
- maytansinoid (DM4) antitubulin payload for potent cytotoxicity.
- cleavable sulfo-SPDB disulfide linker enables controlled intracellular release.
- sulfo modification improves aqueous handling and conjugation efficiency.
- high purity suitable for analytical and development use.
- soluble in DMSO at high concentration for formulation flexibility.
- appropriate for ADC construction, characterization, and analytical standards.
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