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Medchemexpress LLC Sulforaphane | 4478-93-7 | MFCD00016766 | 99.0% | 177.29 | 50 MG
Supplier: Medchemexpress LLC HY1375550MG
Sulforaphane is an orally active inducer of the Keap1/Nrf2/ARE pathway, promoting transcription of tumor-suppressing proteins and inhibiting HDACs. It protects the heart by activating the Keap1/Nrf2/ARE pathway and inducing HO-1 expression, and suppresses high glucose-induced pancreatic cancer via AMPK-dependent signal transmission. It exhibits both anticancer and anti-inflammatory properties.
- Induces cell cycle arrest and apoptosis.
- Inhibits growth re-initiation and decreases cell viability.
- Reduces apoptotic cells and pro-apoptotic proteins.
- Activates Keap1/Nrf2/ARE pathway and induces HO-1 expression.
- Inhibits mammary tumor formation.
- Reduces incidence and weight of DMBA-induced mammary tumors.
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