Cayman Chemical SulforhodamIn BsodIM salt 50mg

Supplier:  Cayman Chemical 3153950 MG

A xanthone with diverse biological activities inhibits fatty acid synthase and HIV-1 protease (IC50s 5 54 and 5 12 M respectively) active against methicillin-sensitive and -resistant S aureus strains (MICs 1 57-12 5 g/ml) inhibits nitric oxide and PGE2 production in LPS-stimulated RAW 264 7 cells (IC50s 12 4 and 11 08 M respectively) a STING agonist that binds to the C-terminal domain of STING (H232 variant) (Kd 137 M) induces expression of an IFN-b-luciferase reporter in HEK293T cells transfected with human STING (H232 variant) at 25 M prevents carrageenan-induced paw edema in mice at 20 mg/kg decreases the viability of LNCaP 22Rv1 DU145 and PC3 prostate cancer cells in vitro (IC50s 5 9 6 9 22 5 and 12 7 M respectively) reduces tumor growth in a 22Rv1 mouse xenograft model at 100 mg/kg

Catalog No. 50-299-1106