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Apexbio Technology LLC Sunitinib malate(Synonyms: Sutent, SU11248, Sunitinib L-malate, Sunitinib malate salt, SU-11248 malate, Sutent malate), 10mM (in 1mL DMSO), CAS: 341031-54-7.
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Supplier:  Apexbio Technology LLC A82555.1

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Sunitinib malate (CAS 341031-54-7) is a small molecule orally bioavailable multitargeted receptor tyrosine kinase inhibitor It inhibits various receptor tyrosine kinases including platelet-derived growth factor receptor (PDGFR) vascular endothelial growth factor receptors (VEGFR-1 2 and 3) c-KIT FLT3 kinase colony-stimulating factor-1 receptor (CSF-1R) and RET kinase In neuroblastoma cell lines (e g SK-N-BE(2) SH-SY5Y LAN-5) treatment with sunitinib malate significantly suppresses proliferation in a dose-dependent manner (IC50 10-20 ng/ml) Preclinical studies show tumor growth inhibition and reduced metastasis in neuroblastoma mouse models highlighting its potential for research in oncology therapeutics

Catalog No. 50-000-60784


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