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Enzo Life Sciences SUPERKILLERTRAIL Protein (soluble) (human), (recombinant) (10µg)
Supplier: Enzo Life Sciences ALX2011153010
Enhanced ligand with improved stability providing significantly enhanced immune activation. SUPERKILLERTRAIL (soluble) (human), (recombinant) is an enhanced ligand that utilizes the Killer™ linker peptide mutated to increase disulfide-mediated cross-linking to form a more stable oligomer. Alternative name: TNFSF 10, Apo-2L, CD253. Concentration: 0.5mg/ml. Endotoxin: <0.01EU/µg purified protein (LAL test). Purity: ≥98% (SDS-PAGE). MS analysis, <1% impurity (mainly Hsp70 protein from E. coli). MW: ~26kDa. Formulation: Liquid. In 20mM HEPES, pH 7.4, containing 150mM sodium chloride, 0.005% Tween 20, 1% sucrose, 1mM DTT. Source: Produced in E. coli. The extracellular domain of human TRAIL (aa 95-281) is fused at the N-terminus to a His-tag and a linker peptide. The active multimeric conformation is stabilized by an inserted mutation allowing an additional CC-bridge. Specificity: Binds to human TRAIL receptors.
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