AdipoGen SuperKillerTRAIL Soluble ms

Supplier:  AdipoGen AG40T00043020

Protein. The extracellular domain of mouse TRAIL aa 99-291 is fused at the N-terminus to a His-tag and a linker peptide. The active multimeric conformation is stabilized by an inserted mutation allowing an additional CC-bridge. Source E. coli. Endotoxin content <0.01EU/µg purified protein LAL test Lonza. Liquid. In 20mM HEPES, pH 7.4, 300mM NaCl, 0.01% Tween 20, 1% sucrose, 1mM DTT. Binds to mouse and less potently to human TRAIL receptors. Purity >95% SDS-PAGE. TNF-related apoptosis-inducing ligand TRAIL Apo2LCD253 TNFSF10 is a type II transmembrane protein of about 34kDa. Like most members of the tumor necrosis factor TNF superfamily of cytokines TRAIL can be cleaved at the cell surface by metalloproteases to form a soluble molecule.

Catalog No. 50-256-2800