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Cayman Chemical Suplatstosylate 50mg

Supplier: Cayman Chemical 3031650 MG

An inhibitor of amyloid-B aggregation inhibits aggregation of monomeric AB42 and induces disaggregation of AB42 fibrils in vitro from 3 1-50 UM reduces AB42-induced toxicity in HT22 cells at 10 UM increases step-through latency in a passive avoidance test and increases spontaneous alteration in the Y-maze compared with vehicle control mice in a mouse model of AB42-induced acute Alzheimers disease at 10 mg/kg decreases brain levels of AB42 and increases spontaneous alteration in the Y-maze in the APP/PS1 transgenic mouse model of Alzheimers disease
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