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Cayman Chemical SureLIghtPE-695 10mg
Supplier: Cayman Chemical 1746510 MG
An atypical antipsychotic an agonist of 5-HT1A receptors (EC50 36.31 nM for inhibition of forskolin-induced adenylate cyclase activity in HeLa cells expressing human receptors) as well as an inverse agonist of 5-HT1D receptors (IC50 2.69 nM) and a partial agonist of 5-HT1B receptors (EC50 6.17 nM) in [35S]GTPYS binding assays an antagonist at 5-HT2A and dopamine D2 receptors (Kis 1.15 and 1.29 nM respectively) in cell-based assays inhibits d-amphetamine-induced hyperactivity and apomorphine-induced stereotypy in rats (ID50s 1.53 and 2.43 mg/kg respectively)
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