Thermo Scientific™ SureSTART™ 2 mL Glass Screw (U)Top HPLC and GC Vials, Level 3

Catalog No.	Color	Material (Coating)	Thread Style	Quantity
03-452-239	Clear	No	9 mm SureStop Short Thread	1000/Pk.
03-452-235	Clear	No	9 mm Short Thread	100/Pk.
03-452-237	Clear	No	9 mm Short Thread	5000/Pk.
03-452-238	Clear	No	9 mm SureStop Short Thread	100/Pk.
03-452-240	Clear	No	9 mm SureStop Short Thread	5000/Pk.
03-452-236	Clear	No	9 mm Short Thread	1000/Pk.
03-452-242	Amber	No	9 mm SureStop Short Thread	100/Pk.
03-452-246	Amber	No	9 mm SureStop Short Thread	5000/Pk.
03-452-244	Amber	No	9 mm SureStop Short Thread	1000/Pk.
03-452-265	Clear	Silanized	9 mm Short Thread	100/Pk.

Catalog No. 03-452-239 Supplier Thermo Scientific™ Supplier No. 6PSV91PSST

Description

For separations that demand reproducible, high-sensitivity results, use SureSTART™ 2 mL Glass Screw Top Vials (Level 3) for high-performance LC-MS and GC-MS analyses.

Key Features

• Silanized version available
• For a secure, leak-free seal, pair with SureSTART™ 9 mm AVCS™ screw caps and septa
• Write-on patch for sample labeling and tracking

Performance Level 3 – for High-Sensitivity Applications

• Identified by three waves on the vial
• Meets US, EU, and JPN Pharmacopeia requirements
• Contain the lowest levels of extractable metals and leachables
• Ideal for GC, LC, and MS applications, including Thermo Scientific™ LC and GC Orbitrap™ MS systems and other HRAM instruments
• Supports workflows that demand consistent sensitivity and selectivity

Specification Certified

• Dimensionally verified for complete autosampler compatibility
• Inspected via automated optical and gauge systems to maintain strict tolerances
• Constructed from uniform, defect-free glass for consistent performance

Lot Traceable

• 100% traceable through the manufacturing process
• Certificate of Conformance available by lot number for audit documentation

Specifications

• Diameter (Metric) Opening: 6 mm
• Color: Clear
• Diameter (Metric) Outer: 12 mm
• Material: Glass
• Sterility: Non-sterile
• Disposable: Single-use
• Volume (Metric): 2 mL
• For Use With (Application): (U)HPLC, GC, MS
• Graduated: Yes
• Insert Type: No
• Material (Coating): No
• Packaging Type: 10 Pks. of 100
• Size (Metric) Opening: 9 mm
• Thread Style: 9 mm SureStop Short Thread
• Volume (Metric) Residual: <170 μL
• Base Style: Outer Base Style: Flat Bottom Inner Base Style: Flat Bottom
• Product Line: SureSTART Level 3
• Volume (Metric) Total: 2 mL
• Closure Type: SureStop Screw Cap
• Quantity: 1000/Pk.
• Closure Size: 9 mm
• Marking Spot: Yes
• Volume (Metric) Usable: 1.5 mL
• For Use With (Equipment): HPLC/GC Autosampler
• Autoclavable: Autoclavable
• Certifications/Compliance: Specification Certified
• Height (Metric): 32 mm
• Product Type: SureStop Screw Thread

Frequently Asked Questions (FAQs)

Are SureSTOP vials compatible with standard autosamplers, or do I need special equipment?

SureSTOP vials are designed for compatibility with nearly every LC or GC autosampler. They are part of the SureSTART family, which is tested for autosampler compatibility and specification certified for physical dimensions.

How do SureSTOP vials help with evaporation control compared to generic vials?

Under stress conditions (e.g., 1.3 mL methanol at 40 °C for 72 h), SureSTOP vials with AVCS closures lose significantly less solvent compared with generic screw-top or even crimp vials. The “definite stop” means the cap is tightened correctly (neither under nor over-tightened) so septum compression is predictable, and cap-tilt or septum displacement (which lead to evaporation paths) are minimized.

In workflows where solvent loss or sample concentration change is critical (as for very low volumes or volatile analytes), SureSTOP vials offer measurable improvement.

What types of applications are SureSTOP vials well-suited for?

SureSTOP vials are well-suited for:
• GC, LC and MS workflows where volatile or semi-volatile solvents are used and evaporation or sample loss is a concern.
• High-sensitivity or trace-analysis workflows where variation in sealing can impact reproducibility.
• Labs where autosampler failures (due to cap/tilt/septum issues) are affecting throughput.

How are SureSTOP vials different from standard screw-top autosampler vials?

Key aspects of SureSTOP vials include:
• The “definite stop” design prevents over-tightening (which might deform the septum or the vial neck) and under-tightening (leading to leaks or evaporation).
• Achieve the best performance with caps that have Advanced Vial Closure System (AVCS) technology that levels and aligns the cap properly, reducing cap tilt and septum displacement.
• Demonstrated lower solvent loss (evaporation) in stressed tests compared with generic vial and closure combinations.

What problems do SureSTOP vials help solve?

The SureSTOP vials are 2 mL screw-thread (9 mm) vials that incorporate a patented “definite stop point” in the vial finish (alignment ring) so when you use them with AVCS (Advanced Vial Closure System) 9 mm screw caps, you cannot under- or over-tighten the closure. This feature helps solve problems such as inconsistent sealing, variable septum compression, vial/septa push through, sample evaporation, or autosampler failures due to poorly sealed vials.

What are SureStop vials?

In addition to the features on standard 2 mL vials, SureStop vials also have a patented definite stop point (alignment ring) in the design of the vial finish. This prevents the vial from being an optimal seal, which eliminates under- and over-sealing by the cap/closure and user-to-user variance.

SureStop vials are designed for use with Advanced Vial Closure System (AVCS) screw caps. They improve transfer reliability and give a more secure liquid seal than standard screw vials. SureStop vials are available as a 2 mL as either clear or amber options and are highly recommended for use with GC and LC applications.