Thermo Scientific™ SureSTART™ 2 mL Glass Screw Top Vials, Level 3 High Performance Applications

Catalog No.	Material	Closure Type	No. per Pack
03-452-239	Clear Glass	SureStop Screw Cap	1000/Pk.
03-452-235	Clear Glass	Short Thread Screw Cap	100/Pk.
03-452-237	Clear Glass	Short Thread Screw Cap	5000/Pk.
03-452-238	Clear Glass	SureStop Screw Cap	100/Pk.
03-452-240	Clear Glass	SureStop Screw Cap	5000/Pk.
03-452-236	Clear Glass	Short Thread Screw Cap	1000/Pk.
03-452-242	Amber Glass	SureStop Screw Cap	100/Pk.
03-452-246	Amber Glass	SureStop Screw Cap	5000/Pk.
03-452-244	Amber Glass	SureStop Screw Cap	1000/Pk.
03-452-265	Clear Silanized Glass	Short Thread Screw Cap	100/Pk.

Catalog No. 03-452-239 Supplier Thermo Scientific™ Supplier No. 6PSV91PSST

Description

Use SureSTART™ 2 mL Glass Screw Top Vials, Performance Level 3, for high performance GC-MS and LC-MS applications.

Choose Thermo Scientific™ SureSTART™ 2 mL Glass Screw Top Vials, Performance Level 3, for high performance applications, when sensitivity is a must. Level 3 vials are designed to protect your most valuable samples and deliver consistent, reproducible results for your most demanding analyses. This offering includes Thermo Scientific™ SureStop™ vials, which, when used with 9 mm AVCS™ screw caps, ensure an optimal seal every time. The SureStop vial-AVCS cap system is specially designed to prevent screw thread vial failures such as cap tilt, cap deformities, dislodged septa, or septum push through, thus preventing injection failures and sample evaporation.

Features

• Available in amber and clear glass
• Specification Certified to ensure their physical dimensions for autosampler compatibility
• Meet all requirements of US, EU, JPN Pharmacopeia
• Buy in bulk for greater savings

Performance Level 3 Vials – for High Performance Applications

• Identified by three waves on the vial
• Convenient write-on patch for many of the vials
• Suitable for GC, HPLC/UHPLC, and mass spectrometry (MS) applications
• Recommended for use with Thermo Scientific™ GC and LC Orbitrap™ MS systems and other high-resolution accurate mass (HRAM) instruments

Specification Certified

• All Thermo Scientific SureSTART vials are dimensionally verified
• Inspected by automated optical and gauge inspection to ensure critical dimensions and tolerances
• Uniform and defect-free

Lot Traceable

• 100% traceable through the manufacturing process
• Certificate of Conformance available by lot number upon request

The SureSTART Performance Levels

SureSTART vials, caps, inserts, septa, and kits are available in three performance levels. Now you can choose the products that best suit your analytical, performance, or budget needs.

• Level 1: Everyday analysis
Chromatography approved
SureSTART Level 1 products are cost optimized, suitable for all instrument types, and quality tested to deliver the performance, sample security, and reproducibility you need for everyday analyses. They are an ideal solution for verifying compound presence and quantification using detection techniques such as UV, RI, and FID.

• Level 2: High-throughput analysis
When robustness and reproducibility are key
SureSTART Level 2 vials have very low metal contents and leachables to ensure that they conform to the high standards you need to meet your regulatory requirements. The septa are conditioned to provide a very low level of chromatographic extractables. These products support routine analyses and deliver high quality data with an uninterrupted workflow.

• Level 3: High performance
When sensitivity is a must
SureSTART Level 3 products are packed in a clean environment according to our own hygiene concept and regulations to protect against contaminating factors. The vials contain the lowest levels of extractable metals and leachables to ensure consistent, reproducible sensitivity and selectivity for the most challenging analytes. The septa are conditioned to provide the lowest level of chromatographic extractables. Choose these products for ultimate method performance and high levels of and sample security and integrity.

All SureSTART vials, closures, and septa are certified to meet physical parameter specifications as part of our manufacturing process.

Specifications

• Material: Clear Glass
• Volume (Metric): 2 mL
• Level: Level 3
• No. per Pack: 1000/Pk.
• Size (Metric) Opening: 9 mm
• Base Style: Flat Base
• Product Line: SureSTART Level 3
• Volume (Metric) Total: 2 mL
• Closure Type: SureStop Screw Cap
• Marking Spot: Yes
• Volume (Metric) Usable: 1.5 mL
• Certifications/Compliance: Specification Certified
• Height (Metric): 32 mm
• Product Type: Screw Thread Vial

Frequently Asked Questions (FAQs)

Are SureSTOP vials compatible with standard autosamplers, or do I need special equipment?

SureSTOP vials are designed for compatibility with nearly every LC or GC autosampler. They are part of the SureSTART family, which is tested for autosampler compatibility and specification certified for physical dimensions.

How do SureSTOP vials help with evaporation control compared to generic vials?

Under stress conditions (e.g., 1.3 mL methanol at 40 °C for 72 h), SureSTOP vials with AVCS closures lose significantly less solvent compared with generic screw-top or even crimp vials. The “definite stop” means the cap is tightened correctly (neither under nor over-tightened) so septum compression is predictable, and cap-tilt or septum displacement (which lead to evaporation paths) are minimized.

In workflows where solvent loss or sample concentration change is critical (as for very low volumes or volatile analytes), SureSTOP vials offer measurable improvement.

What types of applications are SureSTOP vials well-suited for?

SureSTOP vials are well-suited for:
• GC, LC and MS workflows where volatile or semi-volatile solvents are used and evaporation or sample loss is a concern.
• High-sensitivity or trace-analysis workflows where variation in sealing can impact reproducibility.
• Labs where autosampler failures (due to cap/tilt/septum issues) are affecting throughput.

How are SureSTOP vials different from standard screw-top autosampler vials?

Key aspects of SureSTOP vials include:
• The “definite stop” design prevents over-tightening (which might deform the septum or the vial neck) and under-tightening (leading to leaks or evaporation).
• Achieve the best performance with caps that have Advanced Vial Closure System (AVCS) technology that levels and aligns the cap properly, reducing cap tilt and septum displacement.
• Demonstrated lower solvent loss (evaporation) in stressed tests compared with generic vial and closure combinations.

What problems do SureSTOP vials help solve?

The SureSTOP vials are 2 mL screw-thread (9 mm) vials that incorporate a patented “definite stop point” in the vial finish (alignment ring) so when you use them with AVCS (Advanced Vial Closure System) 9 mm screw caps, you cannot under- or over-tighten the closure. This feature helps solve problems such as inconsistent sealing, variable septum compression, vial/septa push through, sample evaporation, or autosampler failures due to poorly sealed vials.

What are SureStop vials?

In addition to the features on standard 2 mL vials, SureStop vials also have a patented definite stop point (alignment ring) in the design of the vial finish. This prevents the vial from being an optimal seal, which eliminates under- and over-sealing by the cap/closure and user-to-user variance.

SureStop vials are designed for use with Advanced Vial Closure System (AVCS) screw caps. They improve transfer reliability and give a more secure liquid seal than standard screw vials. SureStop vials are available as a 2 mL as either clear or amber options and are highly recommended for use with GC and LC applications.